Bill Cosby

Fat Albert / Bill / Mushmouth / Mudfoot Brown (voice)

Jan Crawford

Russell (voice)

Gerald Edwards

Weird Harold (voice)

Eric Suter

Rudy (voice)

Erika Scheimer

Diesel (voice)

Eric Greene

Marshall Franklin (voice)

Kim Hamilton

Marge Franklin / Nurse (voice)

Julius Harris

Mr. Tyrone (voice)

Ty Henderson

Ray Franklin (voice)