Davina McCall and Nicky Campbell return to tell incredible stories of people desperate to find missing family and answer questions that have haunted entire lives. This week features two stories of children searching for their birth mothers after life-changing events - former Scotland footballer Dominic Matteo, who started to search after suffering a life-threatening brain tumour, and a woman, pained with emotion on her wedding day because her birth mother was missing.

Davina McCall and Nicky Campbell present the stories of two people trying to unravel family mysteries, with both looking for a birth parent they have never met. Fifty-seven-year-old quarry worker John Hacking was told that his birth mother left him as a baby in a pram outside a block of flats in Buxton and has been searching for her since he was 17 with no luck, while Debra Spark has never met her Italian father Ernesto, who got together with Debra's mother Olive in Milan in the 1960s.

Davina McCall and Nicky Campbell present the stories of two women trying to find birth parents after half a century apart. Ann Melbourne found her birth mother over a decade ago and now wants to locate her birth father Leslie, who she has limited information about in her adoption paperwork, while Amanda Village is searching for her mother Susan, who gave her up for adoption.

An extraordinary search on behalf of Kate Brown from Portsmouth takes on twists and turns and unveils one missing relative after another. Kate Brown with a foster family and the closest thing she had to a blood relative was her foster brother John, who she was very close to, but while Kate was eventually adopted by the foster family, John was sent back to the care system. Ever since, Kate has been on a mission to find him, and during her research, she made an unexpected discovery.

A man whose only memento of his birth mother and siblings is an old local newspaper article searches for his family, and a mother looks for her only child.

Two siblings who found each other as adults try to trace their older sister, whose existence they only heard of at their mother's funeral.

Louise Stoppani is looking for the father she never knew, having discovered aged seven that the man bringing her up was not her biological dad.

With his 87th birthday approaching, retired merchant seamen Roy David searches for his daughter Cheryl, who he has not seen for nearly 60 years. After meeting his first wife Sylvia in New York while working there, the couple had a daughter, but tensions within the family lead to him separating from his wife, and eventually losing touch. Now, Roy seeks forgiveness from Cheryl and hopes to make amends.