Casey Kasem

Shaggy Rogers (voice)

Frank Welker

Fred Jones / Scooby-Doo / The Centaur (voice)

Grey DeLisle

Daphne Blake / Medusa (voice)

Mindy Cohn

Velma Dinkley (voice)

Mark Hamill

Barge Captain (voice)

Tara Strong

Alexandra Viggi (voice)

James Arnold Taylor

Sonny Les Matines / Guy L'Avorton (voice)

Nick Jameson

Lysander Demas / Scary Looking Man (voice)

Phil LaMarr

Toddy Stickfigger / Cabbie (voice)

Jess Harnell

Lue / Shane Flinty / Constable (voice)