Clive Brook

Sherlock Holmes

Miriam Jordan

Alice Faulkner

Ernest Torrence

Professor James Moriarty

Herbert Mundin

George

Reginald Owen

Dr. Watson

Alan Mowbray

Colonel Gore-King

C. Montague Shaw

Judge

Ivan F. Simpson

Faulkner

Roy D'Arcy

Manuel Lopez (uncredited)

John George

Bird Shop Thug (uncredited)