The quints are full-blown threenagers now, and Danielle and Adam must figure out how to make them more disciplined; Adam tries to balance working from home, but after Ava gets sick, the Busbys make a shocking discovery in their house.

The quints have their first sleepover at the Mills when the Busbys are forced to leave their home for a few days.

Thanksgiving is right around the corner, but celebrating is the last thing on the Busbys' minds; tensions run high between Adam and Danielle as they continue the hunt for a new house and the quints undergo their first school testing.

The Busbys move out of their mold-infested home, but transitioning isn't easy; the quints night time antics escalate until Adam and Danielle split up their bedrooms for the first time; Adam plans a surprise birthday party for Danielle.

As the Busbys navigate life in their new home, Adam and Danielle try to salvage what's left of the Christmas season; when Danielle learns she needs surgery on her wisdom teeth, Adam struggles to keep the house afloat and deliver a perfect Christmas.

Adam gets a great work opportunity, but he needs to rely on the chaotic quints to make it a success; when Parker's anxiety gets the best of her, the Busbys must look for solutions; Blayke follows in her mom's footsteps with a new hobby.

It's a dream come true for the Busby girls as the whole family goes on a Disney cruise but is the cruise ship ready for the Busbys? When Adam gets a huge job offer, it means major changes for the family, causing tension between him and Danielle.

A trip to the Busbys' old home brings a surprise. Adam's job situation faces a new development. Meanwhile, the Busbys brace for bad news at Hazel's eye appointment and Danielle and the Quints come up with a creative way to give back to the NICU.