Christopher Daniel Barnes

Peter Parker / Spider-Man (voice)

Sara Ballantine

Mary Jane Watson (voice)

Ed Asner

J. Jonah Jameson (voice)

Roscoe Lee Browne

Wilson Fisk / Kingpin (voice)

Jennifer Hale

Felicia Hardy (voice)

Linda Gary

Aunt May (voice)

Julie Bennett

Aunt May (voice)

Wanda De Jesus

Doctor Sylvia Lopez (voice)

Mark Hamill

Jason Phillips / Hobgoblin (voice)

Dorian Harewood

Tombstone (voice)