Fran Drescher

Fran Fine (voice)

Charles Shaughnessy

Maxwell Sheffield (voice)

Daniel Davis

Niles (voice)

Lauren Lane

C.C. Babcock (voice)

Nicholle Tom

Maggie Sheffield (voice)

Benjamin Salisbury

Brighton Sheffield (voice)

Madeline Zima

Grace Sheffield (voice)

Pamela Adlon

Chester the Dog (voice)

Maurice LaMarche

The Rain Man (voice)