Shortly before Thanksgiving, a Philadelphia suburb is rocked by the murder of 67-year-old Alice Hufnagle.

In Portsmouth, Va., a 16-year-old ballet dancer is assaulted and murdered in her home, and detectives must investigate her family members as well as her circle of friends.

When a college student is found murdered in his Arlington, Texas, apartment, investigators suspect the kindhearted victim's generosity may have led a killer to his door.

A video tape surfaces after a naval officer is raped and stabbed suggesting the victim may have been silenced to prevent a scandal.

In Fort Pierce, Fla., a tax attorney is found strangled to death, and detectives must scrutinize deadbeat tenants and delinquent clients while hunting for his killer.

When a beloved matriarch is found murdered, her friends and neighbors come under suspicion as detectives investigate the first homicide in the small town of Hubbardston, Mich.

A young Navy wife is found raped and strangled to death in her home near the Mayport Naval Station in Jacksonville, Fla.

An elementary school teacher goes missing after her first day at a new job, and investigators sift through clues to uncover the heartbreaking truth behind her sudden disappearance.

There is no sign of a break-in when 13-year-old Mollie Pittman is attacked and murdered in the Orlando, Fla., home of family friends; it takes investigators 17 years to find out whether she knew her killer.

In La Jolla, Calif., telemarketing manager David Stevens' charred body is found in his burned-out car, and detectives encounter a rogue's gallery of suspects while looking for his killer.

In Stockton, Calif., investigators search for 23-year-old Dalene Carlson who has gone missing, then a tractor operator makes a gruesome discovery in a cornfield.

In 1988, a 9-year-old girl goes missing in Great Falls, Mont.; the case goes cold until a chance encounter at a bus stop breathes new life into the investigation and leads to the horrifying truth behind the girl's disappearance.

Philadelphia investigators bring to light the obsession that drove a suspect to murder student Deborah Wilson, who was found strangled to death in a university computer laboratory without her shoes and socks.