A high school history teacher and family man is arrested, charged with the rape and murder of a female student.

When a man in a wheelchair is found dead in New York Harbor, Assistant District Attorney Kathryn Peale brings a charge of Murder Two against the man's daughter. Jimmy Brogan defends the young woman against the charge.

In the middle of trial, Judge Rubin Wright (Judd Hirsch) is arrested and asks Jimmy to be his lawyer on the spot. Jimmy accepts the case even though he has a rocky past with the stern but well-respected Judge Wright.

NYPD officers responding to a 911 call find Victor Esposito and his wife shot in their living room. Their 16 year-old son Anthony, the only person there, is arrested for their murder. While the police conduct an 11-hour interrogation of Anthony, Anthony's brother Mark hires Jimmy. Jimmy rushes to the Precinct only to arrive moments after Anthony confesses…

A 45-year-old fashion designer is accused of murdering her young boyfriend.

Nothing is as it seems when a dentist is murdered in his own chair - and his "Stepford wife" is accused of the crime. After Jimmy and Kathryn learn that the dentist was doing more than just fixing teeth, they become entangled in lies of their own with Kathryn's mother and Jimmy's ex-wife.

A self-proclaimed psychic (Harold Perrineau) is charged with murder because he knows so much about the crime that the DA's office concludes that he had to have committed it. It's up to the judge (Wayne Knight) to decide.

Kathryn revisits a decade-old shooting after the victim dies of her injuries. Lawyer Lloyd Perlman (Mandy Patinkin) persuaded shooter Ronnie Sotto (Rick Gonzalez) to plead guilty of assault at the time, but the death upgrades the charge to murder. Kathryn now struggles with trying the now-reformed Sotto. And Jimmy, who takes the case as a favor to Perlman, begins to question whether Sotto is guilty of anything.

Jimmy represents an accused killer from his old "Hell's Kitchen" neighborhood, while Kathryn's entire case relies on the testimony of a 12-year-old, special-needs kid with a memory like a camera.