First of a two-part social experiment in which Dr Chris van Tulleken takes over part of a GP surgery and stops patients' prescription pills. He attempt's to tackle a series of specific cases with alternative treatments to see how important the pills really are for the patients. He also tries to combat one of the biggest threats currently facing humanity - antibiotic resistance.

Dr Chris van Tulleken has been trying to treat certain patients without drugs. Now he wants to expand and offer drug-free treatments to all 14,000 patients at the practice.