Jeff Bergman

George Jetson / Mr. Spacely (voice)

Grey DeLisle

Jane Jetson (voice)

Trevor Devall

Elroy Jetson (voice)

Tania Gunadi

Gladys (voice)

Tress MacNeille

Rosie the Robot (voice)

Danica McKellar

Judy Jetson (voice)

Frank Welker

Astro (voice)

Eric Bauza

Rolf Rodriguez (voice)

JB Blanc

Usher Robot (voice)

Will Friedle

Mayor Mercury (voice)