Best friends compete against twin brothers to answer increasingly difficult brain teaser puzzles.

Two golf buddies go head to head against a pair of sorority sisters to answer a series of challenging questions.

Best friends Drew and Charley compete against co-workers Jake and puppeteer Natalia in a series of difficult puzzles.

Twins brothers go head to head against a married couple from the suburbs in a big to win big solving difficult brain teaser puzzles.

A pair of brothers go head to head with two roommates in a bid to win big solving a series of brain teaser puzzles.

Two friends go head to head against a newlywed couple in a bid to win big solving a series of brain teasing puzzles.

Former combat medic Jessica and her childhood best friend Deven compete against Peter who can solve a Rubik's Cube with his feet and his best friend Greg in a series of difficult puzzles.

A pair of teachers compete against two sisters.

Neuroscientist Princess and her best friend Justin compete against co-workers Derek and Tim in a series of difficult puzzles.

American friends compete against a married couple from France to answer increasingly difficult brain teaser puzzles.

Canadian best friends Lynze and Sarah go up against recently engaged couple Amanda and Robert in a series of difficult puzzles.

Beat box brothers compete against dating lawyers to answer increasingly difficult brain teaser puzzles.

Med student Princess and UCLA law graduate Kimberlina are sisters who go up against couple Sarah and Joe in a series of difficult puzzles.

Minister and lawyer Ray and his friend Leah go up against engaged couple Tiffany and Dan in a series of difficult puzzles.

Sisters compete against two friends to answer increasingly difficult brain teaser puzzles.

Trivia besties compete against boss and employee to answer increasingly difficult brain teaser puzzles; host Ben Gleib.

Best friends compete against sisters to answer increasingly difficult brain teaser puzzles; host Ben Gleib.

College friends Nicole and Andrew go up against literature professor Erica and her husband Diego in a series of difficult puzzles.

Amateur mentalist Jeremy and his co-worker Hannah compete against friends Jamie and Taylor in a series of difficult puzzles.

Childhood friends Kelsey and JR compete against married couple Kara and Brandon in a series of difficult puzzles.

MENSA member Justin and his frat brother compete against engaged couple Joe and Jessica in a series of difficult puzzles.

West coast cousins compete against an east coast mother and daughter.

Liberal Democrats compete against conservative Republicans.

Long-time best friends compete against former colleagues to answer increasingly difficult brain teaser puzzles.

A man good at celebrity impressions and his wife compete against a dating couple to answer difficult puzzles.

Comic Ben Gleib hosts as twin sisters compete against best friends to answer increasingly difficult brain teaser puzzles.

A pair of fraternity brothers vs two female best friends to answer increasingly brain teaser puzzles.

A pair of beatbox brothers vs dating lawyers to answer increasingly brain teaser puzzles.

A former beer pong champion and his friend compete against a women's studies major and her friend.

A woman with an IQ of 145 and her roommate compete against two best friends to answer increasingly difficult brain teaser puzzles.

An Iraq War Veteran and his wife compete.

An actor and her friend compete against two best friends.

New Jersey friends compete against an fashion cousins to answer increasingly difficult brain teaser puzzles.

Childhood friends compete against an engaged couple to answer increasingly difficult brain teaser puzzles.

Two sets of friends compete against each other.

Co-workers compete against a married couple.

UCLA graduates compete against USC alumnae to answer increasingly difficult brain teaser puzzles to win.

A spiritual psychologist and her teammate compete against two friends to answer increasingly difficult brain teaser puzzles.

Two singles compete against two moms.

A former pro-football player and his friend compete against married rocket scientists.

Two friends compete against a personal chef and her boyfriend.