Peter Parker is settling into his new balanced life. However, when a mysterious serial killer shows up in New York, his normal life is challenged. Eddie Brock, a war veteran, is diagnosed with a life threatening illness. Dr. Otto Octavious makes him an offer he can't refuse.

Spider-Man and Daredevil team-up to take down Sin-Eater while Eddie's new powers are having some unexpected side affects.

The trail on the copycat has dried up. Peter decides to take his mind off his other life and spend the day at Oscorp with Harry and Mary Jane. However, his normal day takes a turn for the bizarre. Eddie's side effects continue to grow, and Jean makes a startling discovery on the Sin-Eater case.

Jean's death hits Spider-Man back into his old ways. Peter is out for blood. Daredevil tries to help the hero regain focus while a new evil rises to the surface.

The Season Finale is here! Peter Parker faces off against he Sinister Six in an explosive Season Finale. Peter's foe's attack him on a personal level, and the hero must fight harder than ever to save the day!