The series returns to the operating theatres of the Queen Elizabeth Hospital Birmingham. A neurosurgeon has to wake his patient up during an operation to remove his brain tumour.

Consultant Maxillofacial Surgeon Tim Martin and his operating partner Sat Parmar are planning a marathon operation on former police officer Loretta. They believe they are the first UK surgeons to operate on the disease Loretta's suffering from.

Surgeons at Birmingham’s Queen Elizabeth Hospital carry out radical operations to help change patients’ lives, including the hospital’s largest ever removal of excess tissue.

At Birmingham Children’s Hospital, surgeons must transplant a kidney from a father to his two-year-old son, while a three-year-old girl needs a life-changing heart procedure.

A surgeon performs the most complex operation in his field: removing a woman’s oesophagus and using her own stomach to replace it. Another team tackles a hard-to-reach tumour.

Surgeons take on major trauma operations at Birmingham’s Queen Elizabeth Hospital. They have just minutes to save a woman with a life-threatening bleed on her brain.